The Duke Biobank is a resource for clinical and translational researchers to bank or manipulate biospecimens. The four main initiatives in which the Duke Biobank is involved are:

The Index of Biospecimens is a catalog of existing clinical research biological samples at Duke that may be available for sharing.

The LabVantage system is being implemented to serve as Duke's enterprise system for Biobanking Information Management System.

The Biospecimen Repository and Processing Core is Duke's central tissue procurement core in the Department of Pathology and the Duke Cancer Institute.

The DNA Bank (previously the CHG DNA Bank) is a shared resource that specializes in blood and DNA biobanking and blood derivatives.